Everee #3 - Peri-menopause Support

Everee #3 contains Ovitage® the world’s most complete collagen derived from whole ovine skin and produced using a proprietary process that isolates all of the skin's important components, including structural proteins well beyond the collagen I and III common in traditional bovine and marine collagen products. 

This composition is boosted by Livaux®, a scientifically studied prebiotic extracted from gold kiwifruit. The result is a protein powder rich in specific amino acids ideally suited to support the body’s ability to deal with the challenges of perimenopause, from gut health to hair loss, skin health and brain fog. 

Establishing a healthy gut microbiome is essential for gut health, and the connection to skin health through the gut-skin axis is well established. The Livaux® in Everee #3 has been shown in scientific studies to support the gut microbe F. prausnitzii (10), thereby supporting gut health. 

Dropping oestrogen levels reduce the body's ability to produce specific collagens, in particular in the intestinal membranes that may weaken as a result, leading to leaky gut. Supporting the body's ability to make the specific membrane proteins that build this epidermal structure helps combat this symptom of menopause. 

Peptides containing oxidised cystine have been shown to support production of membrane proteins collagen IV and collagen VII (11) and the Ovitage® in Everee #3 has a substantially higher oxidised cystine content than traditional collagens. 

Collagen IV is the junctional protein responsible for joining the layers of the skin together and acting in each hair follicle to anchor hair in the head. As a whole skin extract, the Ovitage® in Everee #3 contains this important collagen type. 

Peptides rich in oxidised cystine have been shown to support collagen IV production in the skin and in the hair follicle and supporting skin firmness as well as follicle health (9) and the Ovitage® in Everee #3 has substantially greater amounts of oxidised cystine than any other collagen or common dietary protein sources such as whey or soy. In addition, collagens, such as Ovitage® have been shown in scientific studies to support skin hydration (12). 

Skin stress during peri menopause arises from hormonal changes as well as oxidative stress from diet and environmental factors. This leads to skin inflammation and redness. 

Peptides rich in oxidised cystine have been shown to support the body's production of taurine and glutathione (5). Taurine produced by the body and supports the body’s response to inflammation through the taurine chloramine pathway (13).

The Ovitage® in Everee Women™ #3 supports this pathway, and the ability of the body to address causes of skin inflammation. Glutathione is known as an important antioxidant produced within skin cells to combat oxidative stress (2). Glutathione production requires cystine and supporting this pathway is possible through  high proteins and peptides rich in cystine protein.

Glutamic acid is a form of glutamate, the most abundant transmitter in the nervous system and essential for healthy brain function and cognitive performance (14, 15). 

The impact of hormonal changes on this essential neurotransmitter have been reported in menopausal studies and good levels of glutamic acid from protein help maintain the appropriate balance of glutamate to support normal brain function (16). 

Studies directly show that increasing tyrosine through short term or long term protein ingestion raises brain tyrosine levels and boosts dopamine (and other catecholamine) production, specifically targeted at actively firing neurons (1). With substantially higher tyrosine than traditional collagen, the Ovitage® in Everee #3 provides the key building blocks for dopamine production and so supports stress and mood.